Publications

HERV-K HML-2 transcriptional profiling and splicing pattern unveiled by direct single-molecule long-read RNA sequencing

Author(s): Mariana Polychronopoulou, Eleni Kyriakou, Filiana Sotiriadou, Magda Bletsa & Gkikas Magiorkinis

Published in: Mobile DNA, 2026 April, ISSN 1759-8753

Publisher: BioMed Central Ltd. (Springer Nature)

DOI: 10.1186/s13100-026-00400-4

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CD169+ and HLA-DR+ extracellular vesicles are highly represented in human plasma and dynamically expressed in SARS-CoV-2 infection and long COVID-associated sequelae

CD169+ and HLA-DR+ extracellular vesicles are highly represented in human plasma and dynamically expressed in SARS-CoV-2 infection and long COVID-associated sequelae

Author(s): Marialaura Fanelli; Vita Petrone; Rossella Chirico; Luigi Coppola; Chiara Sorace; Chiara Cipriani; Giovanni Longo; Marco Girasole; Federica Collacchi; Claudia M. Radu; Martino Tony Miele; Alexandre Lucas; Elisabetta Teti; Vincenzo Malagnino; Marco Iannetta; Fabrice Malergue; Sergio Bernardini; Emanuela Balestrieri; Loredana Sarmati ;Sandro Grelli; Antonella
Minutolo; Claudia Matteucci

Published in: Frontiers in Cellular and Infection Microbiology; 2026 February, ISSN 2235-2988

Publisher: Frontiers Media SA

DOI: 10.3389/fcimb.2026.1686186

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HERV-W ENV transcription in B cells predicting symptomatic COVID-19 and risk for long COVID can express a full-length protein despite stop codon in mRNA from chromosome X via a ribosome readthrough

HERV-W ENV transcription in B cells predicting symptomatic COVID-19 and risk for long COVID can express a full-length protein despite stop codon in mRNA from chromosome X via a ribosome readthrough

Author(s): Joanna Brunel, Julien Paganini, Melissa Galloux, Benjamin Charvet, Hervé Perron

Published in: Microbes and Infection, 2025 July-August, ISSN 1286-4579

Publisher: Elsevier BV

DOI: 10.1016/J.MICINF.2024.105431

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Crosstalk between human endogenous retroviruses and exogenous viruses

Crosstalk between human endogenous retroviruses and exogenous viruses

Author(s): Edoardo Pizzioli, Antonella Minutolo, Emanuela Balestrieri, Claudia Matteucci, Gkikas Magiorkinis, Branka Horvat

Published in: Microbes and Infection, 2025 July-August, ISSN 1286-4579

Publisher: Elsevier BV

DOI: 10.1016/J.MICINF.2024.105427

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Characterization model of the post COVID-19 condition based on immunological, biochemical, and cytokine markers.

Characterization model of the post COVID-19 condition based on immunological, biochemical, and cytokine markers.

Author(s): Bárbara Oliván-Blázquez, Marta Bona-Otal, Fátima Méndez-López, David Lerma-Irureta, Paula García-Izuel, Jesús Ibáñez-Ruiz, Alberto Montolío, María Ruiz-Herreros, Javier Godino, Beatriz Jimeno-Beltran, María del Mar Encabo-Berzosa, Izaskun Arenaz, Ana Medel-Martínez, Verónica Casado-Vicente, Mayte Coiras, Carlos Tellería-Orriols, Jon Schoorlemmer, Rosa Magallón-Botaya

Published in: iScience, Issue 27, 2024 Aug, ISSN 2589-0042

Publisher: Elsevier BV

DOI: 10.1016/J.ISCI.2024.110839

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Flow cytometry for extracellular vesicle characterization in COVID-19 and post-acute sequelae of SARS-CoV-2 infection

Flow cytometry for extracellular vesicle characterization in COVID-19 and post-acute sequelae of SARS-CoV-2 infection

Author(s): Marialaura Fanelli; Vita Petrone; Rossella Chirico; Claudia Maria Radu; Antonella Minutolo; Claudia Matteucci

Published in: Extracellular Vesicles and Circulating Nucleic Acids, 2024 August, ISSN 2767-6641

Publisher: OAE Publishing Inc

DOI: 10.20517/EVCNA.2024.20

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Limitations of current high-throughput sequencing technologies lead to biased expression estimates of endogenous retroviral elements.

Limitations of current high-throughput sequencing technologies lead to biased expression estimates of endogenous retroviral elements

Author(s): Konstantina Kitsou, Aris Katzourakis, Gkikas Magiorkinis

Published In: NAR Genomics and Bioinformatics, Issue 6, 2024 July, ISSN 2631-9268

Publisher: Oxford University Press (OUP)

DOI: 10.1093/NARGAB/LQAE081

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Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC individuals: the potential contribution of different COVID-19 pandemic waves

Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC individuals: the potential contribution of different COVID-19 pandemic waves

Author(s): Marialaura Fanelli, Vita Petrone, Christian Maracchioni, Rossella Chirico, Chiara Cipriani, Luigi Coppola, Vincenzo Malagnino, Elisabetta Teti, Chiara Sorace, Marta Zordan, Pietro Vitale, Marco Iannetta, Emanuela Balestrieri, Guido Rasi, Sandro Grelli, Fabrice Malergue, Loredana Sarmati, Antonella Minutolo, Claudia Matteucci

Published In: Current Research in Microbial Sciences, Issue 6, 2023 December 12, ISSN 2666-5174

Publisher: Elsevier BV

DOI: 10.1016/J.CRMICR.2023.100215

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International Journal of Molecular Sciences

Preliminary Evidence of the Differential Expression of Human Endogenous Retroviruses in Kawasaki Disease and SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in Children

Author(s): Balestrieri E., Corinaldesi E., Fabi M., Cipriani C., Giudice M., Conti A., Minutolo A., Petrone V., Fanelli M., Miele MT., Andreozzi L., Guida F., Filice E., Meli M., Grelli S., Rasi G., Toschi N., Torcetta F., Matteucci C., Lanari M., Sinibaldi-Vallebona P.

Published in: Int J Mol Sci, Issue Int J Mol Sci, 2023 October, ISSN 1422-0067

Publisher: Multidisciplinary Digital Publishing Institute (MDPI)

DOI: 10.3390/ijms242015086

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Expression profile of HERVs and inflammatory mediators detected in nasal mucosa as a predictive biomarker of COVID-19 severity

Expression profile of HERVs and inflammatory mediators detected in nasal mucosa as a predictive biomarker of COVID-19 severity

Author(s): Petrone, V, Fanelli, M.L, Giudice M., Toschi, N., Conti, A., Maracchioni, C., Ianetta, M., Resta, C., Cipriani, C., Miele, M.T., Amati, F., Andreoni, M., Sarmati, L., Rogliani, P., Novelli, G., Garaci, E., Rasi, G., Sinibaldi Vallebona, P., Minutolo, A.,

Published In: Frontiers in Microbiology, Issue 22:14:1155624, 2023 May, ISSN 1664-302X

Publisher: Frontiers Media

DOI: 10.3389/fmicb.2023.1155624

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SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients

SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients

Author(s): B.Charvet, J.Brunel, J.Pierquin, M.Iampietro, D.Decimo, N.Queruel, A.Lucas, M.del Mar Encabo-Berzosa, I.Arenaz, T.P.Marmolejo, A.Gonzalez, A.C.Maldonado, C.Mathieu, P.Kury, J.Flores-Rivera, F.Torres-Ruiz, S.Avila-Rios, G.Salgado Montes de Oca,

Published in: iScience, Issue Volume 26 issue 11, 2023 May, ISSN 2589-0042

Publisher: Cell Press

DOI: 10.1016/j.isci.2023.106604

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About it

x-mol.net | s4me.info | reddit.com | europepmc.org | unmc.edu

Thymosin alpha 1 restores the immune homeostasis in lymphocytes during Post-Acute sequelae of SARS-CoV-2 infection

Thymosin Alpha 1 restores the immune Homeostasis in lymphocytes during Post-Acute sequelae of SARS-CoV-2 infection

Author(s): A. Minutolo, V. Petrone, M. Fanelli, C. Maracchioni, M. Giudice, E. Teti, L. Coppola, C. Sorace, M. Iannetta, M.T. Miele, S. Bernardini, A. Mastino, P. Sinibaldi Vallebona, E. Balestrieri, M. Andreoni, L. Sarmati, S. Grelli, E. Garaci, C. Matteucci

Published In: Int Immunopharmacology, Issue 118:110055, 2023 May, ISSN 1878-1705

Publisher: ELSEVIER

DOI: 10.1016/j.intimp.2023.110055

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Characterization of COVID-19 and post-acute sequelae of SARS-CoV-2 infection cohort study: the role of CD169 as a biomarker of systemic dysfunction and its alteration respect to SARS-CoV-2 pandemic waves’

Characterization of COVID-19 and post-acute sequelae of SARS-CoV-2 infection cohort study: the role of CD169 as a biomarker of systemic dysfunction and its alteration respect to SARS-CoV-2 pandemic waves’

Author(s): Christian Maracchioni

Published in: IRIS, 2023 January

Publisher: UNITOV

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Multidistrict Host–Pathogen Interaction during COVID-19 and the Development Post-Infection Chronic Inflammation

Multidistrict Host–Pathogen Interaction during COVID-19 and the Development Post-Infection Chronic Inflammation

Author(s): Fanelli, M.; Petrone, V.; Buonifacio,M. Delibato,NE.; Balestrieri, E.; Grelli, S.; Minutolo,A.; Matteucci,C

Published in: Pathogens, Issue 1198, 2022 October, ISSN 2076-0817

Publisher: MDPI

DOI: 10.3390/pathogens11101198

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High CD169 Monocyte/Lymphocyte Ratio Reflects Immunophenotype Disruption and Oxygen Need in COVID-19 Patients

High CD169 Monocyte/Lymphocyte Ratio Reflects Immunophenotype Disruption and Oxygen Need in COVID-19 Patients

Author(s): Minutolo A., Petrone V., Fanelli M., Iannetta M., Giudice M., Ait Belkacem I., Zordan M., Vitale P., Rasi G., Sinibaldi-Vallebona P., Sarmati L., Andreoni M., Malergue F., Balestrieri E., Grelli S., Matteucci C.

Published in: Pathogens, Vol. 10, Issue 12, 2021 December, Article 1639, ISSN 2076-0817

Publisher: MDPI AG

DOI:10.3390/pathogens10121639

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Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patients

Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patients

Author(s): Balestrieri E., Minutolo A., Petrone V., Fanelli M., Iannetta M., Malagnino V., Zordan M., Vitale P., Charvet B., Horvat B., Bernardini S., Garaci E., di Francesco P., Sinibaldi Vallebona P., Sarmati L., Grelli S., Andreoni M., Perron H., Matteucci C.

Published in: EBioMedicine, Vol. 66, 2021 April, Article 103341, ISSN 2352-3964

Publisher: Elsevier B.V.

DOI:10.1016/j.ebiom.2021.103341

Read more

Publications

HERV-K HML-2 transcriptional profiling and splicing pattern unveiled by direct single-molecule long-read RNA sequencing

Author(s): Mariana Polychronopoulou, Eleni Kyriakou, Filiana Sotiriadou, Magda Bletsa & Gkikas Magiorkinis

Published in: Mobile DNA, 2026 April, ISSN 1759-8753

Publisher: BioMed Central Ltd. (Springer Nature)

DOI: 10.1186/s13100-026-00400-4

CD169+ and HLA-DR+ extracellular vesicles are highly represented in human plasma and dynamically expressed in SARS-CoV-2 infection and long COVID-associated sequelae

Published in: Frontiers in Cellular and Infection Microbiology; 2026 February, ISSN 2235-2988

Publisher: Frontiers Media SA

DOI: 10.3389/fcimb.2026.1686186

HERV-W ENV transcription in B cells predicting symptomatic COVID-19 and risk for long COVID can express a full-length protein despite stop codon in mRNA from chromosome X via a ribosome readthrough

Author(s): Joanna Brunel, Julien Paganini, Melissa Galloux, Benjamin Charvet, Hervé Perron

Published in: Microbes and Infection, 2025 July-August, ISSN 1286-4579

Publisher: Elsevier BV

DOI: 10.1016/J.MICINF.2024.105431

Crosstalk between human endogenous retroviruses and exogenous viruses

Author(s): Edoardo Pizzioli, Antonella Minutolo, Emanuela Balestrieri, Claudia Matteucci, Gkikas Magiorkinis, Branka Horvat

Published in: Microbes and Infection, 2025 July-August, ISSN 1286-4579

Publisher: Elsevier BV

DOI: 10.1016/J.MICINF.2024.105427

Characterization model of the post COVID-19 condition based on immunological, biochemical, and cytokine markers.

Published in: iScience, Issue 27, 2024 Aug, ISSN 2589-0042

Publisher: Elsevier BV

DOI: 10.1016/J.ISCI.2024.110839

Flow cytometry for extracellular vesicle characterization in COVID-19 and post-acute sequelae of SARS-CoV-2 infection

Author(s): Marialaura Fanelli; Vita Petrone; Rossella Chirico; Claudia Maria Radu; Antonella Minutolo; Claudia Matteucci

Published in: Extracellular Vesicles and Circulating Nucleic Acids, 2024 August, ISSN 2767-6641

Publisher: OAE Publishing Inc

DOI: 10.20517/EVCNA.2024.20

Limitations of current high-throughput sequencing technologies lead to biased expression estimates of endogenous retroviral elements

Author(s): Konstantina Kitsou, Aris Katzourakis, Gkikas Magiorkinis

Published In: NAR Genomics and Bioinformatics, Issue 6, 2024 July, ISSN 2631-9268

Publisher: Oxford University Press (OUP)

DOI: 10.1093/NARGAB/LQAE081

Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC individuals: the potential contribution of different COVID-19 pandemic waves

Published In: Current Research in Microbial Sciences, Issue 6, 2023 December 12, ISSN 2666-5174

Publisher: Elsevier BV

DOI: 10.1016/J.CRMICR.2023.100215

Preliminary Evidence of the Differential Expression of Human Endogenous Retroviruses in Kawasaki Disease and SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in Children

Author(s): Balestrieri E., Corinaldesi E., Fabi M., Cipriani C., Giudice M., Conti A., Minutolo A., Petrone V., Fanelli M., Miele MT., Andreozzi L., Guida F., Filice E., Meli M., Grelli S., Rasi G., Toschi N., Torcetta F., Matteucci C., Lanari M., Sinibaldi-Vallebona P.

Published in: Int J Mol Sci, Issue Int J Mol Sci, 2023 October, ISSN 1422-0067

Publisher: Multidisciplinary Digital Publishing Institute (MDPI)

DOI: 10.3390/ijms242015086

Expression profile of HERVs and inflammatory mediators detected in nasal mucosa as a predictive biomarker of COVID-19 severity

Author(s): Petrone, V, Fanelli, M.L, Giudice M., Toschi, N., Conti, A., Maracchioni, C., Ianetta, M., Resta, C., Cipriani, C., Miele, M.T., Amati, F., Andreoni, M., Sarmati, L., Rogliani, P., Novelli, G., Garaci, E., Rasi, G., Sinibaldi Vallebona, P., Minutolo, A.,

Published In: Frontiers in Microbiology, Issue 22:14:1155624, 2023 May, ISSN 1664-302X

Publisher: Frontiers Media

DOI: 10.3389/fmicb.2023.1155624

SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients

Author(s): B.Charvet, J.Brunel, J.Pierquin, M.Iampietro, D.Decimo, N.Queruel, A.Lucas, M.del Mar Encabo-Berzosa, I.Arenaz, T.P.Marmolejo, A.Gonzalez, A.C.Maldonado, C.Mathieu, P.Kury, J.Flores-Rivera, F.Torres-Ruiz, S.Avila-Rios, G.Salgado Montes de Oca,

Published in: iScience, Issue Volume 26 issue 11, 2023 May, ISSN 2589-0042

Publisher: Cell Press

DOI: 10.1016/j.isci.2023.106604

About it

Thymosin Alpha 1 restores the immune Homeostasis in lymphocytes during Post-Acute sequelae of SARS-CoV-2 infection

Author(s): A. Minutolo, V. Petrone, M. Fanelli, C. Maracchioni, M. Giudice, E. Teti, L. Coppola, C. Sorace, M. Iannetta, M.T. Miele, S. Bernardini, A. Mastino, P. Sinibaldi Vallebona, E. Balestrieri, M. Andreoni, L. Sarmati, S. Grelli, E. Garaci, C. Matteucci

Published In: Int Immunopharmacology, Issue 118:110055, 2023 May, ISSN 1878-1705

Publisher: ELSEVIER

DOI: 10.1016/j.intimp.2023.110055

Characterization of COVID-19 and post-acute sequelae of SARS-CoV-2 infection cohort study: the role of CD169 as a biomarker of systemic dysfunction and its alteration respect to SARS-CoV-2 pandemic waves’

Author(s): Christian Maracchioni

Published in: IRIS, 2023 January

Publisher: UNITOV

Multidistrict Host–Pathogen Interaction during COVID-19 and the Development Post-Infection Chronic Inflammation

Author(s): Fanelli, M.; Petrone, V.; Buonifacio,M. Delibato,NE.; Balestrieri, E.; Grelli, S.; Minutolo,A.; Matteucci,C

Published in: Pathogens, Issue 1198, 2022 October, ISSN 2076-0817

Publisher: MDPI

DOI: 10.3390/pathogens11101198

High CD169 Monocyte/Lymphocyte Ratio Reflects Immunophenotype Disruption and Oxygen Need in COVID-19 Patients

Author(s): Minutolo A., Petrone V., Fanelli M., Iannetta M., Giudice M., Ait Belkacem I., Zordan M., Vitale P., Rasi G., Sinibaldi-Vallebona P., Sarmati L., Andreoni M., Malergue F., Balestrieri E., Grelli S., Matteucci C.

Published in: Pathogens, Vol. 10, Issue 12, 2021 December, Article 1639, ISSN 2076-0817

Publisher: MDPI AG

DOI:10.3390/pathogens10121639

Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patients

Author(s): Balestrieri E., Minutolo A., Petrone V., Fanelli M., Iannetta M., Malagnino V., Zordan M., Vitale P., Charvet B., Horvat B., Bernardini S., Garaci E., di Francesco P., Sinibaldi Vallebona P., Sarmati L., Grelli S., Andreoni M., Perron H., Matteucci C.

Published in: EBioMedicine, Vol. 66, 2021 April, Article 103341, ISSN 2352-3964

Publisher: Elsevier B.V.

DOI:10.1016/j.ebiom.2021.103341